Scream Cream


Scream Cream is a combination of prescription drug products that have been formulated into a hypoallergenic cream. It contains vasodilators commonly used to treat heart conditions or migraines, however in this preparation and application they work synergistically to enhance female sex drive and sexual stimulation. The active ingredients relax vascular smooth muscles, causing peripheral blood vessels (especially veins) to dilate, which promotes peripheral pooling of blood to the area applied. The preparation is applied to the clitoris or external genitalia 15-30 minutes before intercourse and works by increasing blood flow to the local area. Topically applied sildenafil has been reported to improve libido, vaginal moisture, and sexual satisfaction in women.1 



How Supplied

This preparation is not commercially available and must be compounded for patients that would benefit from its administration as determined by a prescriber. Common formulations prepared at Galleria Medical Pharmacy include but are not limited to:

 Sildenafil Citrate 20 mg/mL / Aminophylline 30 mg/mL / L-Arginine 60 mg/mL Cream

 Aminophylline 30 mg/mL / L-Arginine 60 mg/mL Cream

 Sildenafil Citrate 10 mg/mL / Aminophylline 30 mg/mL / L-Arginine 60 mg/mL Cream / Ergoloid Mesylate 0.5 mg/mL / Pentoxifylline 50 mg/mL Cream

 Sildenafil Citrate 10 mg/mL / Aminophylline 30 mg/mL / Ergoloid Mesylate 0.5 mg/mL / Pentoxifylline 50 mg/mL Cream


Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.


  1. Boswell-Smith V, Spina D, Page CP. Phosphodiesterase inhibitors. Br J Pharmacol. 2006;147 Suppl 1(Suppl 1):S252 S257.
  2. Schmidt DT, Watson N, Dent G, et al. The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways. Br J Pharmacol. 2000;131(8):1607-1618. doi:10.1038/sj.bjp.0703725.

Compounding Pharmacy Statement

This preparation is compounded with drug components whose suppliers are registered with the FDA. While Galleria Medical Pharmacy adheres to USP <795> guidelines and applicable state and federal regulations to meet the required quality standards, the statements made regarding this preparation have not been evaluated by the FDA for safety or clinical effectiveness. As such, this preparation is not intended to diagnose, treat, cure, or prevent any disease. For inquiries concerning this preparation, please contact (504) 267-9876.